Both are common; it is mostly about what you cut and your space. A vertical wire (towers side by side, wire upright, foam pushed through horizontally) is the classic wing-cutter layout: gravity does not sag the wire along its length, and long span panels sit naturally. A horizontal wire (wire flat, foam below, gantry overhead) feels like a router/3D-printer and is intuitive for tall blocks and lettering.
Mechanically they are equivalent — same X/Y per end. Pick the one that matches your typical stock and bench. https://cncfoam.com uses the convention Z = tower spacing, Y = up/down, X = front/back depth, and you can orient the result either way.
Mechanically they are equivalent — same X/Y per end. Pick the one that matches your typical stock and bench. https://cncfoam.com uses the convention Z = tower spacing, Y = up/down, X = front/back depth, and you can orient the result either way.